Interdisciplinary Stress Physiology (DSP ISP)

DSP sujet

Abstract

The DSP-ISP is focused on high quality research and education on stress responses from the cellular to the systemic level. 

Stress, seen as adaptive responses to environmental challenges (stressors), was central to survival of each individual and, thus, relevant for selection processes during evolution. Therefore, all organisms - from the unicellular to the multicellular organisms, from algae to mammals - share fundamental response patterns to stressors.  Accordingly, the DSP-ISP will evaluate the common physiological mechanisms across species as well as species specific variations. The main perspectives are on energy-, oxygen, and metal-induced stress responses as well as on the impact of stress hormones on cognitive processing and emotional memory.

 

The following topics will be addressed:  

  • 1. Oxidative protein modification.
    Stress-induced protein modification and changes in protein activity leading to altered functions in ion channel activity, transport systems and the nutritional state of the cell.
  • 2. Autophagy, vesicular transport and exocytosis.
    Stress response (oxidative and metal stress) will be analyzed in cultured mammalian and plant cells focusing on the role of autophagy, exocytosis and exosome release. 
  • 3. Lipid sensing.
    Lipid droplets are important components in starvation-induced metabolic stress, serving as “energy source” for lipid breakdown by lipophagy. Lipid droplets as modulators of cellular stress reactions and programmed cell death will be investigated.
  • 4. Stress models.
    Cell differentiation associated with stress responses will be investigated by using in-vitro as well as in-vivo stress models.  
  • 5. Stress hormones and cognitive / emotional processing
    Stress hormones, including cortisol and adrenalin, will be quantified and correlated with cognitive performance and emotional memory in humans during mental stress induction and related to molecular mechanisms.
  • News
    Unfortunately, the planned lecture on 17th December 2020 by Univ.-Prof. Dr. Matthias NEUMAYR (Vice President of the Supreme Court of Justice of the Republic of Austria; University of Salzburg) on ​​the subject of "Five Years of the EuErbVO: Recent Developments in International Inheritance Law" cannot take place due to the continuing Covid19 situation
    Ingrid Vukusic and Georg Zimmermann were awarded the Hans-Stegbuchner Prize for outstanding scientific work in the Department of Mathematics at the University of Salzburg on the 19th November 2020.
    The Paris Lodron University of Salzburg has launched an in-house mentoring program for new students as part of the “On Track” project. And it has come at the right time, because the lockdown has made the start of their studies into a real challenge for many first-semester students.
    The recording of the PLUS Talks "Studies and Teaching WS 2020/21“ from 25.11.2020 is now available.
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    24 very easy exercises on 24 cards can be found in the SALTO advent calendar. The exercise ideas are ideal for children from the age of three and are also easy for the whole family to carry out in a small space. With the support of the Kinder Büro (Children's Office), this combinable contribution should benefit as many as possible.
    Researchers led by Salzburg's geoinformatics scientist Christian Neuwirth had already developed and presented a mathematical model for Covid-19 in May 2020 which examines the question of how long and intensively social distancing measures have to be maintained in order to reduce corona deaths further.
    Results of the study on media use by children and families during lockdown. Home schooling could be improved, but is on the right track. Secondary schools have a better profile. Families have learned to deal with lockdown and homeschooling.
    Digitization has led to an enormous spread of different forms of mobile working. Corona has brought an additional boost and has introduced home office in areas and for activities that were previously unimaginable.
    During the time of Corona, in particular, it became clear just how important it is to support students digitally in their every day university life. The project „On Track“ – stay on track combines digital and social worlds. It is starting at the right time!
  • Veranstaltungen
  • 04.12.20 Adventkalender der Universitätsbibliothek Salzburg 2020
    04.12.20 Ideen mit Methode
    05.12.20 Adventkalender der Universitätsbibliothek Salzburg 2020
    06.12.20 Adventkalender der Universitätsbibliothek Salzburg 2020
    07.12.20 Adventkalender der Universitätsbibliothek Salzburg 2020
    08.12.20 Adventkalender der Universitätsbibliothek Salzburg 2020
    09.12.20 Adventkalender der Universitätsbibliothek Salzburg 2020
    10.12.20 Adventkalender der Universitätsbibliothek Salzburg 2020
    10.12.20 Ideen mit Methode
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