Organic Chemistry and NMR Spectroscopy for Protein Research

 

Bild Chemical synthesis

Proteins are key players in all cellular processes and their correct (normal) function is prerequisite for a healthy cell. The umpteen roles of proteins include, among others, the regulation of gene expression, the transport of molecules and ions across cell membranes, and the catalysis of reactions (which otherwise would be too slow). Once one or more proteins start to behave abnormally, uncontrolled events occur in the cells, which dramatically raises the risk of developing pathologies.

Protein modifications (spontaneous or enzyme-mediated) are often dysregulated in diseases. The deep understanding of the mode of action of proteins under healthy and pathological conditions is necessary for the development of modern and efficient strategies in the diagnosis and therapy of diseases. In particular, (bio)organic chemistry and NMR spectroscopy largely contribute to this “mission” by reproducing, mimicking, manipulating target biomolecules, elucidating their structure, and providing artificial modulators of their function.

 

  • News
    Further information about teaching at PLUS
    The most important information on the changes to research services at the University of Salzburg.
    Distance learning for exchange students and the completion of courses from overseas.
    As issued by the responsible authority, the Rectorate has decided to take the following measures in the area of studying to help prevent the further spread of SARS CoV-2 infections:
  • Veranstaltungen
  • Alumni Club
  • PRESS
  • Uni-Shop
  • University of Salzburg's facebook site University of Salzburg's twitter site University of Salzburg's instagram site University of Salzburg's flickr site University of Salzburg's vimeo site