Die AG Cabrele

Publikationen

Abbildung 1941195.JPG

 

peer-reviewed publications

Complete NMR assignment of succinimide, its detection and quantification in peptides and intact proteins, L. Grassi, C. Regl, S. Wildner, G. Gadermaier, C.G. Huber, C. Cabrele, M. Schubert, accepted (2017) Analytical Chemistry.

Two Distinct Conformations in Bet v 2 Determine Its Proteolytic Resistance to Cathepsin S, W.T. Soh, P. Briza, E. Dall, C. Asam, M. Schubert, S. Huber, L. Aglas, B. Bohle, F. Ferreira, 
H. Brandstetter (2017) Int. J. Mol. Sci. 18, 2156.

Targeting of a helix-loop-helix transcriptional regulator by a short helical peptide, C. Roschger, S. Neukirchen, B. Elsässer, M. Schubert, N. Maeding, T. Verwanger, B. Krammer, C. Cabrele (2017) ChemMedChem 12, 1497–1503.

A secondary structure element present in a wide range of fucosylated glycoepitopes, T. Aeschbacher, M. Zierke, M. Smiesko, Beat Ernst, M. Collot, J.-M. Mallet, F. H.-T. Allain, M. Schubert (2017) Chemistry - A European Journal 23, 11598-11610.

Impact of the amino acid sequence on the conformation of side chain lactam-bridged octapeptides, S. Neukirchen, V. Krieger, C. Roschger, M. Schubert, B. Elsässer, C. Cabrele  (2017) J. Pept. Sci 23, 587-596.

Inhibition of delta-secretase improves cognitive functions in mouse models of Alzheimer’s disease, Z. Zhang, O. Obianyo, E. Dall, J. Du, H. Fu, X. Liu, S.S. Kang, M. Song, S.-P. Yu, C. Cabrele M. Schubert, X. Li, J.-Z. Wang, H. Brandstetter, K. Ye (2017)
Nature Communications 8, 14740.

Dimerization of the fungal defense lectin CCL2 is essential for its toxicity against nematodes, S. Bleuler-Martinez, K. Stutz, R. Sieber, M. Collot, J.-M. Mallet, M. O. Hengartner, M. Schubert*, A. Varrot*, M. Künzler* (2017) Glycobiology 24, 486-500.

Straightforward Solvothermal Synthesis toward Phase Pure Li2CoPO4F, J. Schoiber, R.J.F. Berger, J. Bernardi, M. Schubert, C. Yada, H. Miki, N. Husing (2016) Crystal Growth & Design 16, 4999-5005.

Structural basis for sulfation-dependent self-glycan recognition by the human immune- inhibitory receptor Siglec-8, J. M. Propster, F. Yan, B. Ernst, F.H.-T. Allain, M. Schubert (2016) Proc. Natl. Acad. Sci. USA 113, E4170-9.

Posttranslational Modifications of Intact Proteins Detected by NMR Spectroscopy: Application to Glycosylation, M. Schubert*, M.J. Walczak*, M. Aebi, G. Wider (2015)
Angew. Chemie Int. Ed. 54, 7096-7100.

Functional Siglec lectin domains from soluble expression in the cytoplasm of Escherichia coli, J. M. Propster, F. Yan, B. Ernst, F.H.-T. Allain, M. Schubert (2015) Protein Expr. Purif. 109, 14-22.

Stabilization of the dimeric birch pollen allergen Bet v 1 impacts its immunological properties, S. Kofler, C. Ackaert, M. Samonig, C. Asam, P. Briza, J. Horejs-Hoeck, C. Cabrele, F. Ferreira, A. Duschl, C. Huber, H. Brandstetter (2014) J. Biol. Chem. 289: 540-551. doi: 10.1074/jbc.M113.518795.

Replacement of Thr32 and Gln34 in the C-terminal neuropeptide Y fragment 25-36 by cis-cyclobutane and cis-cyclopentane β-amino acids shifts selectivity toward the Y(4) receptor, L. Berlicki, M. Kaske, R. Gutiérrez-Abad, G. Bernhardt, O. Illa, R. M.Ortuño, C. Cabrele, A. Buschauer, O. Reiser (2013) J. Med. Chem. 56, 8422-8431. doi: 10.1021/jm4008505.

Biomimetic Soluble Collagen Purified from Bones, A. M. Ferreira, P. Gentile, S. Sartori, C. Pagliano, C. Cabrele, V. Chiono, G. Ciardelli (2012) Biotechnol. J. doi: 10.1002/biot.201200184.

Copper Nanoparticles Stabilized on Nitrogen-doped Carbon Nanotubes as Efficient and Recyclable Catalysts for Alkyne/Aldehyde/Cyclic Amine A3-Type Coupling Reactions, V. Ganga Ramu, A. Bordoloi, T.C. Nagaiah, W. Schuhmann, M. Muhler, C. Cabrele (2012) Appl. Cat. A Gen. 431-432, 88-94 (http://dx.doi.org/10.1016/j.apcata.2012.04.019).

Unique α,β- and α,α,β,β-Peptide Foldamers Based on cis-β-Aminocyclo-pentanecarboxylic Acid, L. Berlicki, L. Pilsl, E. Weber, I. M. Mandity, C. Cabrele, T. A. Martinek, F. Fülöp, O. Reiser (2012) Angew. Chemie Int. Ed. 51, 2208-2212.

How Ionic Liquids Can Help to Stabilize Native Proteins, H. Weingärtner, C. Cabrele, C. Herrmann (2011) Phys. Chem. Chem. Phys. 14, 415-426.

Functional Reconstitution of Human Neuropeptide Y (NPY) Y2 and Y4 Receptors in Sf9 Insect Cells, N. Pop, P. Igel, A. Brennauer, C. Cabrele, G. Bernhardt, R. Seifert, A. Buschauer (2011) J. Recept. Signal Transduct. 31, 271-285.

Side-Chain Cyclization Based on Serine Residues: Synthesis, Structure and Activity of a Novel Cyclic Analogue of the Parathyroid Hormone Fragment 1-11, A. Caporale, M. Sturlese, L. Gesiot, F. Zanta, A. Wittelsberger, C. Cabrele, (2010) J. Med. Chem. 53, 8072-8079.

G protein-coupled receptors function as logic gates for nanoparticle binding and cell uptake, W. Hild, K. Pollinger, A. Caporale, C. Cabrele, M. Keller, N. Pluym, A. Buschauer, R. Rachel, J. Tessmar, M. Breunig, A. Goepferich, (2010) Proc. Natl. Acad. Sci. USA 107, 10667-10672.

Synthesis and Conformation of an Analog of the Helix-Loop-Helix Domain of the Id1 Protein Containing the O-Acyl Iso-Prolyl-Seryl Switch Motif, M. Beißwenger, T. Yoshiya, Y. Kiso, C. Cabrele, (2010) J. Peptide Sci. 16, 303-308.

Synthetic Peptides Containing a Conserved Sequence Motif of the Id Protein Family Modulate Vascular Smooth Muscle Cell Phenotype, S. Pellegrino, N. Ferri, N. Colombo, E. Cremona, A. Corsini, R. Fanelli, M. L. Gelmi, C. Cabrele, (2009) Bioorg. Med. Chem. Lett. 19, 6298-6302.

Stable Right- and Left-handed Peptide Helices Containing Cα-tetrasubstituted α-Amino Acids, A. A. Grauer, C. Cabrele, M. Zabel, B. König (2009) J. Org. Chem. 74, 3718-3726.

Switching from the Unfolded to the Folded State of the Helix-Loop-Helix Domain of the Id Proteins Based on the O-Acyl Isopeptide Method, S. D. Kiewitz, T. Kakizawa, Y. Kiso, C. Cabrele (2008) J. Peptide Sci. 14, 1209-1215.

Recognition of the Helix-Loop-Helix Domain of the ld Proteins by an Artificial Luminescent Metal Complex Receptor, S. D. Kiewitz, M. Kruppa, A. Riechers, B. König, C. Cabrele (2008) J. Mol. Recognit. 21, 79-88.

Determination of Affinity and Activity of Ligands at the Human Neuropeptide Y Y4 Receptor by Flow Cytometry and Aequorin Luminescence, R. Ziemek, E. Schneider, A. Kraus, C. Cabrele, A. G. Beck-Sickinger, G. Bernhardt, A. Buschauer (2007) J. Rec. Signal Trans. 27, 217-233.

γ-Aminoadamantanecarboxylic Acids Through Direct C–H Bond Amidations, L. Wanka,C. Cabrele, M. Vanejews, P. R. Schreiner (2007) Eur. J. Org. Chem. 9, 1474-1490.

An Improved Synthesis of 3,4-(Aminomethano)proline and its Incorporation into Small Oligopeptides, F. Brackmann, N. Colombo, C. Cabrele, A. de Meijere (2006) Eur. J. Org. Chem. 19, 4440-4450.

Fluorescence- and Luminescence-based Methods for the Determination of Affinity and Activity of Neuropeptide Y Y2 Receptor Ligands, R. Ziemek, A. Brennauer, E. Schneider, C. Cabrele, A. G. Beck-Sickinger, G. Bernhardt, A. Buschauer (2006) Eur. J. Pharmacol. 551, 10-18.

5-Fluorouracil-related Enhancement of Adenoviral Infection Is Coxsackievirus-Adenovirus Receptor Independent and Associated with Morphological Changes in Lipid Membranes, C. Cabrele, M. Vogel, P. Piso, M. Rentsch, J. Schröder, K. W. Jauch, H. J. Schlitt, A. W. Beham (2006) World J. Gastroenterol. 12, 5168-5174.

A Short Id2 Protein Fragment Containing the Nuclear Export Signal Forms Amyloid-Like Fibrils, N. Colombo, J. Schroeder, C. Cabrele (2006) Biochem. Biophys. Res. Commun. 346, 182-187.

Stepwise Solid-Phase-Synthesis and Spontaneous Homodimerization of the Helix-Loop-Helix Protein Id3, J. Svobodová, C. Cabrele (2006) ChemBioChem 7, 1164-1168.

Synthesis and Conformational Analysis of Id2 Protein Fragments: Impact of Chain Length and Point Mutations on the Structural HLH Motif, N. Colombo, C. Cabrele (2006) J. Peptide Sci. 12, 550-558.

Chemoenzymatic Resolution of Epimeric Cis 3-Carboxycyclopentylglycine Derivatives, C. Cabrele, F. Clerici, R. Gandolfi, M. L. Gelmi, F. Molinari, S. Pellegrino (2006) Tetrahedron 62, 3502-3508.

Synthesis and Conformational Properties of Protein Fragments Based on the Id Family of DNA-Binding and Cell-Differentiation Inhibitors, S. Kiewitz, C. Cabrele (2005) Biopolymers (Peptide Sci.) 80, 762-774.

Analogues of Neuropeptide Y Containing ß-Aminocyclopropane Carboxylic Acids are the Shortest Linear Peptides That are Selective for the Y1 Receptor, N. Koglin, C. Zorn, R. Beumer, C. Cabrele, C. Bubert, N. Sewald, O. Reiser, A. G. Beck-Sickinger (2003) Angew. Chem. Int. Ed. 42, 202-205.

Ala31-Aib32: Identification of the Key Motif for High Affinity and Selectivity of Neuropeptide Y at the Y5-Receptor, C. Cabrele, H. A. Wieland, N. Koglin, C. Stidsen, A. G. Beck-Sickinger (2002) Biochemistry 41, 8043-8049.

Redox-Active Cyclic Bis(cysteinyl)peptides as Catalysts for in vitro Oxidative Protein Folding, C. Cabrele, S. Fiori, S. Pegoraro, L. Moroder (2002) Chem. Biol. 9, 731-740.

Photomodulation of the Redox and Folding Adjuvant Properties of Bis-Cysteinyl-Peptides, C. Cabrele, A. Cattani-Scholz, C. Renner, R. Behrendt, D. Oesterhelt, L. Moroder (2002) Eur. J. Org. Chem. 13, 2144-2150.

Photoresponsive Cyclic Bis-Cysteinyl-Peptides as Catalysts of Oxidative Protein Folding, A. Cattani-Scholz, C. Renner, C. Cabrele, R. Behrendt, D. Oesterhelt, L. Moroder (2002) Angew. Chem. Int. Ed. 41, 289-292.

Y-Receptor Affinity Modulation by the Design of Pancreatic Polypeptide/Neuropeptide Y Chimera Led to Y5-Receptor Ligands with Picomolar Affinity, C. Cabrele, H. A. Wieland, M. Langer, C. Stidsen, A. G. Beck-Sickinger (2001) Peptides 22, 365-378.

Characterization of Neuropeptide Y Receptor Subtypes by Synthetic NPY Analogues and by Anti-Receptor Antibodies, C. P. Eckard, C. Cabrele, H. A. Wieland, A. G. Beck-Sickinger (2001) Molecules 6, 448-467.

Binding Properties of Three Neuropeptide Y Receptor Subtypes from Zebrafish: Comparison with Mammalian Y1 Receptors, M. M. Berglund, I. Lundell, C. Cabrele, C. Serradeil-Le Gal; A. G. Beck-Sickinger, D. Larhammar (2000) Biochem. Pharmacol. 60, 1815-1822.

Differently Labeled Peptide Ligands for Rapid Investigation of Receptor Expression on a New Human Glioblastoma Cell Line, M. Fabry, C. Cabrele, H. Höcker, A. G. Beck-Sickinger (2000) Peptides 21, 1885-1893.

2-36[K4, RYYSA19-23]PP: A Novel Y5-Receptor Preferring Ligand with Strong Stimulatory Effect on Food Intake, K. McCrea, T. Wisialowski, C. Cabrele, B. Church, A. G. Beck-Sickinger, E. Kraegen, H. Herzog (2000) Regul. Pept. 87, 47-58.

The First Selective Agonist for the Neuropeptide Y Y5-Receptor Increases Food Intake in Rats, C. Cabrele, M. Langer, R. Bader, H. A. Wieland, H. N. Doods, O. Zerbe, A. G. Beck-Sickinger (2000) J. Biol. Chem. 275, 36043-36048.

Molecular Characterization of the Ligand-Receptor Interactions of the NPY/PP Family, C. Cabrele, A. G. Beck-Sickinger (2000) J. Peptide Sci. 6, 97-122.

The Synthesis of Diastereo- and Enantiomerically Pure β-Aminocyclopropane-Carboxylic Acids, R. Beumer, C. Bubert, C. Cabrele, O. Vielhauer, M. Pietzsch, O. Reiser (2000) J. Org. Chem. 65, 8960-8969.

The Amino Acid Side Chain Attachment Approach and its Application to the Synthesis of Tyrosine-Containing Cyclic Peptides, C. Cabrele, M. Langer, A. G. Beck-Sickinger (1999) J. Org. Chem. 64, 3453-4361.

Novel Strategies for the Synthesis of Peptides Containing Cis- or Trans-β-Aminocyclopropanecarboxylic Acids, C. Bubert, C. Cabrele, O. Reiser (1997) Synlett, 827-829.

Aggregation and Conformational Transition in Aqueous Solution of a Bombolitin III Analogue Containing a Photoreactive Side-Chain Group, C. Cabrele, S. Furin, M. Gurrath, S. Mammi, E. Schievano, E. Peggion (1997) Biopolymers 42, 147-156.

Investigation of Crudes of Synthesis of [Leu31, Pro34]-Neuropeptide Y by Capillary Zone Electrophoresis/Mass Spectrometry, A. Zaramella, O. Curcuruto, M. Hamdan, C. Cabrele, E. Peggion (1995) Rapid Commun. in Mass Spectrometry 9, 1386-1390.

publications in scientific magazines

Wenn Proteine ihren Partner wechseln (When proteins chainge their partner), C. Cabrele (2011) BIOSpektrum (Spektrum Akademischer Verlag) 1, 12.

publications in books and proceedings

Insights into carbohydrate recognition by 3D structure determination of protein- carbohydrate complexes using NMR, M. Schubert, in: K. Kato adn T. Peters (Eds), NMR in Glycoscience and Glycotechnology New Developments in NMR , 17 May (2017). RSC Books.

Peptide-Based Modulation of Helix-Loop-Helix Proteins, C. Cabrele, S. Pellegrino, N. Ferri, M. L. Gelmi, M. Beißwenger (2010) in Abstracts of Papers, 239th ACS National Meeting, San Francisco, CA, USA, ORGN-478.

Conformation and Stability of the Helix-Loop-Helix Domain of the Id Protein Family, S. D. Kiewitz, Y. Kiso, C. Cabrele, (2009) in Breaking Away: Proceedings of the 21st American Peptide Symposium, M. Lebl Ed., 462-463, American Peptide Society, Bloomington, Indiana.

Synthesis and Activity of Cyclic Analogues of PTH(1-11), A. Caporale, F. Zanta, C. Cabrele, A. Wittelsberger, E. Peggion (2008) in Proceedings of the 30th European Peptide Symposium; H. Lankinen Ed., 72-73, EPS and FIPS, Helsinki, Finland.

Synthesis of Fluorescence-Labeled Fragments of the Inhibitors of DNA-Binding Id and Their Characterization by FRET Spectroscopy, C. Cabrele, J. Svobodova, N. Colombo, A. Snyder (2007) in Abstracts of Papers, 233rd ACS National Meeting, Chicago, IL, USA, ORGN-017.

A Synthetic and Spectroscopic Approach to Study the Conformational Properties of the Inhibitor of DNA-binding Id3, J. Svobodova, C. Cabrele (2006) in Proceedings of the International Conference of 43rd Japanese Peptide Symposium and 4th Peptide Engineering Meeting 43JPS/PEM4, Yokohama, H. Ishida & H. Mihara, Ed., 278, The Japanese Peptide Society, Osaka, Japan, 2006.

Studies on the Chemical Synthesis of the Id Proteins and Mutated Analogs, C. Cabrele, S. Kiewitz, J. Havrdova, N. Colombo (2005) in Abstracts of Papers, 230th ACS National Meeting, Washington, DC, USA, ORGN-560.

E4 Mutierte und E4 deletierte Adenoviren zeigen vergleichbare lytische Kapzität wie Onyx 1520 unabhängig vom p53 Status bei kolorektalen Tumorzelllinien, C. Cabrele, M. Vogel, M. Rentsch, A. Fürst, K. W. Jauch, A. Beham (2003) in Chirurgisches Forum, Deutsche Gesellschaft für Chirurgie, Springer Verlag, Heidelberg, Band 32, 75-77.

Synthesis, Redox and Structural Properties of Cystine-Cyclopeptides Containing the Active-Site of the Thioredoxin Superfamily, C. Cabrele, S. Fiori, S. Pegoraro, L. Moroder (2001) in Peptides: The Wave of the Future, M. Lebl & R. A. Houghten, Ed., 462-463, American Peptide Society, San Diego, CA.

NMR Structure of the First Neuropeptide Y Y5-Receptor-Selective Agonist, R. Bader, G. Rytz, C. Cabrele, G. Folkers, O. Zerbe, A.G. Beck-Sickinger (2001) in Peptides 2000, J. Martinez & J. A. Fehrentz, Ed., 449-450, EDK, Paris, France.

Synthesis, Spectroscopic and Biological Studies of Neuropeptide Y Analogs Containing 2-Amino-3-Methoxycarbonyl-1-Cyclopropane-carboxylic Acid, C. Cabrele, R. Beumer, M. Langer, O. Reiser, A. G. Beck-Sickinger (2001) in Peptides 2000, J. Martinez & J. A. Fehrentz, Ed., 795-796, EDK, Paris, France.

Neuropeptide Y: A Molecule for Hunger, Stress and Memory, A. G. Beck-Sickinger, C. Cabrele, R. Söll (1999) in Bioorganic Chemistry: Highlights and New Aspects, U. Diederichsen, T. K. Lindhorst, B. Westermann, L. A. Wessjohann, Ed., 291-297, Wiley-VCH, Weinheim, 1999.

Amino Acid Side-Chain Attachment: A Convenient Strategy to Obtain C-Terminal Modified or Cyclic Peptides by Solid Phase Synthesis, C. Cabrele, A. G. Beck-Sickinger (1999) in Peptides 1998, S. Bajusz and F. Hudecz, Ed., 202-203, Akadémiai Kiadó, Budapest, 1999.

patents

Immunogens Comprising Conformationally Discriminating Epitopes to Produce FcgRIIb- or FcgRIIa-Binding Antibodies for Diagnosis and Therapy of Neoplastic, Infectious, Immune and Autoimmune Diseases, R. Huber, P. Sondermann, U. Jacob, K. Wendt, C. Cabrele, L. Moroder (2005) PCT Int. Appl., 57 pp. CODEN: PIXXD2 WO 2005051999 A2 20050609.

  • News
    Der diesjährige Dissertationspreis ging an den Mathematiker Dr. Markus Hittmeir für seine überragende Arbeit zum Faktorisierungsproblem.
    Die Österreichische Akademie der Wissenschaften vergab am 10. Dezember ihre diesjährigen Preise für exzellente Leistungen in der Forschung. Dipl. Ing. Dr. Volker Ziegler vom Fachbereich Mathematik wurde mit dem Edmund und Rosa Hlawka-Preis für Mathematik prämiert.
    Im Juli 2018 wurde dem internationalen Forschungsprojekt "Processing Instruction for L3 English: Differences between balanced and unbalanced bilinguals? (PI-BI-L3)" die Finanzierung durch das österreichische Bundesministerium für Bildung, Wissenschaft und Forschung (BMBWF) und das mazedonische Ministerium für Bildung und Forschung (MON) vom österreichischen Austauschdienst (OeAD) Wettbewerb für 24 Monate (Laufzeit: 01.07.2018 - 30.06.2020) zugesprochen.
    Im Rahmen der Filmreihe "Filmclub Horizonte" zeigt das Salzburger Filmkulturzentrum "Das Kino" am Giselakai 11 in Salzburg am 13.12.18 und am 10.1.19 die beiden Filme "Leto" und "Breaking the Limits".
    Dienstag, 18. Dezember 2018, 12:15 - 15:00 Uhr, HS 101 der Katholisch-Theologischen Fakultät (Universitätsplatz 1, Salzburg, EG) - Thema: Praxis als Anstoß zur Erkenntnis
    zugunsten von DEBRA Austria - Hilfe für die Schmetterlingskinder
    „Stille Nacht, heilige Nacht“ - ein Lied geht um die Welt: Am 24. Dezember 1818 stimmten Joseph Mohr und Franz Xaver Gruber zum ersten Mal „Stille Nacht, heilige Nacht“ in Oberndorf bei Salzburg an. Von hier nahm das Lied seinen Weg rund um die Welt und wird heute zu Weihnachten von rund zwei Milliarden Menschen in über 300 Sprachen und Dialekten gesungen.
    Tagung "Gleichheit in Europa" aus Anlass des 100. Jahrestages der Einführung des Frauenwahlrechts in Zentral- und Westeuropa
  • Veranstaltungen
  • 16.12.18 „Stille Nacht, heilige Nacht“ - ein Lied geht um die Welt
    17.12.18 „Stille Nacht, heilige Nacht“ - ein Lied geht um die Welt
    17.12.18 zugunsten von DEBRA Austria - Hilfe für die Schmetterlingskinder
    18.12.18 „Stille Nacht, heilige Nacht“ - ein Lied geht um die Welt
    18.12.18 zugunsten von DEBRA Austria - Hilfe für die Schmetterlingskinder
    19.12.18 „Stille Nacht, heilige Nacht“ - ein Lied geht um die Welt
    19.12.18 zugunsten von DEBRA Austria - Hilfe für die Schmetterlingskinder
    20.12.18 „Stille Nacht, heilige Nacht“ - ein Lied geht um die Welt
    20.12.18 zugunsten von DEBRA Austria - Hilfe für die Schmetterlingskinder
    20.12.18 "Probabilistic Laws from Deterministic Dynamics"
    21.12.18 „Stille Nacht, heilige Nacht“ - ein Lied geht um die Welt
    21.12.18 zugunsten von DEBRA Austria - Hilfe für die Schmetterlingskinder
    22.12.18 „Stille Nacht, heilige Nacht“ - ein Lied geht um die Welt
  • Alumni Club
  • PRESSE
  • Uni-Shop
  • VERANSTALTUNGSRÄUME
  • STELLENMARKT
  • Facebook-Auftritt der Universität Salzburg Twitter-Auftritt der Universität Salzburg Instagram-Auftritt der Universität Salzburg Flickr-Auftritt der Universität Salzburg Vimeo-Auftritt der Universität Salzburg