VASCULAR & EXERCISE BIOLOGY UNIT

 

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The scope of our team is to connect modern animal biology and medical applications in the field of vascular-, muscle- and performance research. This covers both, fundamental- and applied research. The research focus of our team which consists of 3 researchers, 2 technical assistants as well as doctoral- and master students is twofold.

The vascular focus covers basic research on blood vessel development and regression in the African Clawed Toad, Xenopus leavis as model organism and biomedical research on coronary bypass surgery, tumor-vascularization and the study of cannabinoid (THC) effects on the skin and the reproductive system. Our group is one of the worldwide leaders in the field of vascular corrosion casting. Besides in vascular corrosion casting we are experts in scanning electron microscopy, 3D morphometry, histology, PCR and intravital microscopy. Cooperations exist with industry, international research facilities and with clinics of the Paracelsus Medical University of Salzburg (PMU).

Our focus in performance biology basically concentrates on adaptive processes of the musculo-skeletal system, being induced by physical training, trauma, extracorporal shock waves, genetic effects, aging or death. The scope of these studies is to gain fundamental knowledge on involved molecular and cellular events, to establish training protocols in preventing aging dependent deterioration of the appropriate tissues as well as in terms of therapeutic tasks, and to provide routine methods to delimitate the time since death being applied in forensic medicine. Research projects are in co-operation with the Department of Forensic Medicine, the Department of Sport Sciences & Kinesiology, and the PMU. Methods comprise histo- and immunocytochemistry, transmission electron microscopy, in situ-hybridization, image analyses, as well as molecular biological approaches.


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