RECOMBINANT ALLERGENS: APPLICATIONS IN ALLERGY DIAGNOSIS AND THERAPY

The primary interest of our group is the development of new tools for allergy diagnosis and for safer and more efficient allergen-specific immunotherapy.

Type I allergies, which comprise a wide range of IgE-mediated disorders such as hay fever, asthma, atopic dermatitis, affect more than 20% of the population and therefore represents a major health problem.

Presently, we are working on birch pollen and associated food allergies, allergic reactions to mountain and Japanese cedar and ragweed and mugwort pollen allergies. To generate improved tools for allergy diagnosis and therapy, our ongoing projects involve:

  • Identification of natural allergens
  • Generation of low IgE binding hypoallergenic molecules in bacterial, yeast and plant expression systems
  • Protein purification
  • Physicochemical protein characterization (analysis of protein folding and aggregation, mass spectrometry)
  • Immunologic characterization of recombinant proteins in vitro
  • Antigen uptake and processing
  • Analysis of allergenic molecules in pre-clinical models

Barrierefreiheit: Kurzbeschreibung des Bildes

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EAACI explains vaccinations

To vaccinate or not to vaccinate? This question raises a great deal of discussion. To find out what a group of international scientists and experts of the immune system have to say about it, take a look at our short and informative animated video.

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Barrierefreiheit: Kurzbeschreibung des Bildes

The research group is part of the international FWF Doktoratskolleg "Immunity in Cancer and Allergy" (ICA) of the University of Salzburg The research group is member of the "Allergy-Cancer-BioNano Research Centre" of the University of Salzburg.

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    Lecture in English. The new series of lectures "Music & Medicine" presents scientific and artistic contributions from leading international experts from various disciplines. The interactions and mechanisms between experience, processing and the psychophysiological effects music can have on people will be examined to understand how music and can promote health and well being.
    01.09.-12.09.2020, https://ditact.ac.at. Due to the current pandemic situation the ditact_womens IT summer studies of the University of Salzburg will take place a week later than planned, from the 01.09.-12.09.2020. Most of the courses will be held online.
    The botanical gardens of the University of Salzburg will reopen on the 2nd June. Normal opening times will apply from the 2nd June.
    The Vice Rectorate for Research, Nicola Hüsing, received five thousand face masks, which were donated by Gebrüder Woerle Ges.m.b.H. in keeping with the motto „SHARING is CARING“ . The face masks were given out to the employees of the University of Salzburg.
    Due to the current situation personal contact with the Psychological Counseling Center is not possible at the moment. We are however available by e-mail, telephone, chat or video chat. Unfortunately, our normal range of workshops cannot take place in the usual way. We would however like to offer the following webinars as an alternative.
    We are gradually learning how to adapt to the Corona outbreak, both in our everyday lives as well as at the university. For us, this means changing to online teaching for the duration of the current semester. Courses and exams held in lecture halls and seminar rooms will not be possible, with exception to some special exams. Regulations for this are currently being drawn up; exceptions are also to be made for selected laboratory exercises and practical sports courses.
    Information of 23rd April 2020: The Minister of Science’s new ruling on special regulations for study law at universities has now been announced, which gives us the opportunity to regulate some important matters. Please note that these regulations have been set for a limited time period (i.e. for this semester, but sometimes even beyond this).
    Current information on labour law at PLUS
    The most important information on the changes to research services at the University of Salzburg.
    Distance learning for exchange students and the completion of courses from overseas.
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    28.05.20 Ökonomien des Mutterleibs (Veranstaltungsreihe 'Physiologien')
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