Research Groups

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Fritz Aberger
The group studies signaling pathways in malignant cancer stem cells responsible for tumor growth, metastasis and disease relapse with the aim to develop treatments that eradicate cancer stem cells by targeted therapy and reactivation of the anti-tumoral immune response.

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Hans Brandstetter
The group studies the structure and function of protein complexes in proteolysis and peptide ligation. We exploit this mechanistic understanding to address important questions such as the immune recognition of molecules, with relevance in allergy and cancer.

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Chiara Cabrele

Elucidation of protein-protein interactions meets drug design for a synergistic approach to cancer research. Looking at proteins of interest (e.g., DNA transcription regulators) at the atomic level, the group reproduces natural structures into synthetic architectures whose function matches/counteracts the native one.

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Albert Duschl
The topics of the group cover nanoparticles and human health, principles of bio-nano interaction, nanosafety, complexes between  nanoparticles and allergens, as well as signal transduction and gene expression in the immune system, regulated by NLR, TLR and cytokine receptors.

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Fatima Ferreira
The group investigates how allergens and allergen source-derived factors shape TH2-biased immune responses. Our major aims are to decipher the mechanisms of allergic sensitization to pollen and to translate basic findings into novel approaches to allergy prevention and therapy.

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Iris Gratz

The work group studies the function of T cells in the skin, with the aim to elucidate the generation of suppressive, regulatory T cells in autoimmunity, and the role of skin resident T cells in skin wound healing and skin cancer.

 

 

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Richard Greil
The tumor microenvironment in chronic lymphocytic leukemia

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Tanja Hartmann

Leukemia cell migration and microenvironment signal integration

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Christian Huber

The team focuses its activities toward the establishment of experimental and computational workflows for cancer and allergy models by untargeted "-omics" analyses, which aims at generating unbiased hypotheses for studying molecular mechanisms of allergy and cancer.

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Nicola Hüsing

The group synthesizes tailor-made inorganic-organic (hybrid) nanomaterials (particles, film, etc.). Starting from deliberately designed precursor molecules, the structure and composition of the from sol-gel processes resulting synthetic nanomaterials is investigated to obtain a deeper insight in synthesis-structure- property relationships.

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Angela Risch

The work group focusses on genetic and epigenetic variations and aberrations in the context of cancer, with the aim of identifying biomarkers of exposure or diagnostic/prognostic markers, as well as new mechanisms in carcinogenesis.

 

 

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Silja Wessler

Infections with Helicobacter pylori are associated with inflammation and gastric cancer. The research of the group focuses on sophisticated mechanisms of pathogen-host interactions which require a complex network of bacterial effector proteins, proteases, etc. interfering with host cell functions and signal transduction pathways.

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Josef Thalhamer
The group develops novel approaches for the treatment of allergies including RNA and DNA vaccines, epicutaneous vaccination, and nanoparticle formulations. In this context, we explore the role of immune cells in the skin and the influence of fold-stability of proteins on immunogenicity and allergenicity.

Speaker of ICA

in memoriam

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Gernot Achatz

Gernot died in August 2011
ICA lost an excellent immunologist and most popular teacher
We lost a friend, but we will keep him alive in our hearts 

 

 

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