Publications of ICA Students

2017

Kurtaj A, Hillebrand C, Fichtinger G, Hattinger E, Lietzenmayer M, Machado Y, Scheiblhofer S, Stoecklinger A, Thalhamer T, Suessner S, Danzer M, Keplinger S, Weinberger J, Schaller S, Winkler S, Gabriel C, Thalhamer J, Weiss R. " Natural protective immunity against grass pollen allergy is maintained by a diverse spectrum of response types." (2017) J Allergy Clin Immunol.

Strandt H, Pinheiro DF, Kaplan DH, Wirth D, Gratz I, Hammerl P, Thalhamer J, Stoecklinger A. " Neoantigen Expression in Steady-State Langerhans Cells Induces CTL Tolerance" (2017) J Immunol.

Scheiblhofer S, Laimer J, Machado Y, Weiss R, Thalhamer J. "Influence of protein fold stability on immunogenicity and its implications for vaccine design." (2017) Expert Rev Vaccines

Yoan Machado, Sanne Duinkerken, Veronika Hoepflinger, Melissa Mayr, Evgeniia Korotchenko, Almedina Kurtaj, Isabel Pablos, Markus Steiner, Angelika Stoecklinger, Joyce Lübbers, Maximillian Schmid, Uwe Ritter, Sandra Scheiblhofer, Michael Ablinger, Verena Wally, Sarah Hochmann, Anna M Raninger, Dirk Strunk, Yvette van Kooyk, Josef Thalhamer, Richard Weiss (2017). Synergistic effects of dendritic cell targeting and laser-microporation on enhancing epicutaneous skin vaccination efficacy. Journal of Controlled Release

Aberger F, Hutterer E, Sternberg C, Del Burgo PJ, Hartmann TN. Acute myeloid leukemia - strategies and challenges for targeting oncogenic Hedgehog/GLI signaling. (2017) Cell Commun Signal.

Greil R, Hutterer E, Hartmann TN, Pleyer L. Reactivation of dormant anti-tumor immunity - a clinical perspective of therapeutic immune checkpoint modulation. (2017) Cell Commun Signal

Schwarz H, Gornicec J, Neuper T, Parigiani MA, Wallner M, Duschl A, Horejs-Hoeck J. Biological Activity of Masked Endotoxin. (2017)  Sci Rep.

Wessler S, Krisch LM, Elmer DP, Aberger F. From inflammation to gastric cancer - The importance of hedgehog/GLI signaling in Helicobacter pylori-induced chronic inflammatory and neoplastic diseases. (2017) Cell Commun Signal

Scheiblhofer S, Laimer J, Machado Y, Weiss R, Thalhamer J. Influence of protein fold stability on immunogenicity and its implications for vaccine design. (2017) Expert Rev Vaccines

Aberger F, Hutterer E, Sternberg C, Del Burgo PJ, Hartmann TN. Acute myeloid leukemia - strategies and challenges for targeting oncogenic Hedgehog/GLI signaling. (2017) Cell Commun Signal. 

Schwarz H, Gornicec J, Neuper T, Parigiani MA, Wallner M, Duschl A, Horejs-Hoeck J. Biological Activity of Masked Endotoxin. (2017) Scientific Reports

2016

Scheiblhofer S, Machado Y, Feinle A, Thalhamer J, Hüsing N, Weiss R. Potential of nanoparticles for allergen-specific immunotherapy - use of silica nanoparticles as vaccination platform. (2016) Expert Opin Drug Deliv.

Radauer-Preiml I, Andosch A, Hawranek T, Luetz-Meindl U, Wiederstein M, Horejs-Hoeck J, Himly M, Boyles MSP, Duschl A. Nanoparticle–allergen interactions mediate human allergic responses: protein corona characterization and cellular responses. (2016) Particle and Fibre Toxicology.

Gruber W, Hutzinger M, Elmer DP, Parigger T, Sternberg C, Cegielkowski L, Zaja M, Leban J, Michel S, Hamm S, Vitt D, Aberger F. "DYRK1B as therapeutic target in Hedgehog/GLI-dependent cancer cells with Smoothened inhibitor resistance". (2016) Oncotarget

Schneider P, Müller A, Gabernet G, Posselt G, Wessler S, Hiss JA, Schneider G. "Hybrid Network Model for "Deep Learning" of Chemical Data: Application to Antimicrobial Peptides". (2016) Mol Inform.

Radauer-Preiml I, Andosch A, Hawranek T, Luetz-Meindl U, Wiederstein M, Horejs-Hoeck J, Himly M, Boyles MSP, Duschl A. "Nanoparticle–allergen interactions mediate human allergic responses: protein corona characterization and cellular responses". (2016) Particle and Fibre Toxicology.

Shihui Guo, W. Skala, V. Magdolen, P. Briza, M. L. Biniossek, O. Schilling, J. Kellermann, H. Brandstetter and P. Goettig. "A Single Glycan at the 99-Loop of Human Kallikrein-related Peptidase 2 Regulates Activation and Enzymatic Activity” (2016)  J Biol Chem.

Krenn PW, Hofbauer SW, Pucher S, Hutterer E, Hinterseer E, Denk U, Asslaber D, Ganghammer S, Sternberg C, Neureiter D, Aberger F, Wickström SA, Egle A, Greil R, Hartmann TN. "ILK induction in lymphoid organs by a TNFα-NF-κB-regulated pathway promotes the development of chronic lymphocytic leukemia.” (2016) Cancer Res.

W. Gruber, M. Hutzinger, D. P. Elmer, T. Parigger, C. Sternberg, L. Cegielkowski, M. Zaja, J. Leban, S. Michel, S. Hamm, D. Vitt and F. Aberger. "DYRK1B as therapeutic target in Hedgehog/GLI-dependent cancer cells with Smoothened inhibitor resistance" (2016) Oncotarget

Moraes AH, Asam C, Batista A, Almeida FC, Wallner M, Ferreira F, Valente AP. "(1)H, (13)C and (15)N resonance assignments and second structure information of Fag s 1: Fagales allergen from Fagus sylvatica." (2016) Biomol NMR Assign 

Pablos I, Wildner S, Asam C, Wallner M, Gadermaier G. "Pollen Allergens for Molecular Diagnosis." (2016) Curr Allergy Asthma Rep

2015

Ganghammer S, Gutjahr J, Hutterer E, Krenn PW, Pucher S, Zelle-Rieser C, Jöhrer K, Wijtmans M, Leurs R, Smit MJ, Gattei V, Greil R, Hartmann TN, "Combined CXCR3/CXCR4 measurements are of high prognostic value in chronic lymphocytic leukemia due to negative cooperativity of the receptors” (2015) Haematologica

Asam, C., H. Hofer, M. Wolf, L. Aglas and M. Wallner. "Tree Pollen Allergens-an Update from a Molecular Perspective." (2015) Allergy

Freier, R., E. Dall and H. Brandstetter. "Protease Recognition Sites in Bet V 1a Are Cryptic, Explaining Its Slow Processing Relevant to Its Allergenicity." (2015) Sci Rep 5

Maier, E., M. Mittermeir, S. Ess, T. Neuper, A. Schmiedlechner, A. Duschl and J. Horejs-Hoeck. "Prerequisites for Functional Interleukin 31 Signaling and Its Feedback Regulation by Suppressor of Cytokine Signaling 3 (Socs3)." (2015) J Biol Chem

Stoehr, L. C., C. Endes, I. Radauer-Preiml, M. S. Boyles, E. Casals, S. Balog, M. Pesch, A. Petri-Fink, B. Rothen-Rutishauser, M. Himly, M. J. Clift and A. Duschl. "Assessment of a Panel of Interleukin-8 Reporter Lung Epithelial Cell Lines to Monitor the Pro-Inflammatory Response Following Zinc Oxide Nanoparticle Exposure under Different Cell Culture Conditions." (2015) Part Fibre Toxicol 

Hattinger E, Scheiblhofer S, Roesler E, Thalhamer T, Thalhamer J, and Weiss R.  "Prophylactic mRNA vaccination against allergy confers long-term memory responses and persistent protection in mice." (2015) J Immunol Res 

Machado Y, Freier R, Scheiblhofer S, Thalhamer T, Mayr M, Briza P, Grutsch S, Ahammer L, Fuchs JE, Wallnoefer HG, Isakovic A, Kohlbauer V, Hinterholzer A, Steiner M, Danzer M, Horejs-Hoeck J, Ferreira F, Liedl KR, Tollinger M, Lackner P, Johnson CM, Brandstetter H, Thalhamer J, and Weiss R. "Fold-stability during endolysosomal acidification is a key factor for allergenicity and immunogenicity of the major birch pollen allergen." (2015) J Allergy Clin Immunol 

Regina Freier, Elfriede Dall, Hans Brandstetter. "Protease recognition sites in Bet v 1a are cryptic, explaining its slow processing relevant to its allergenicity" (2015) Scientific Reports 

Wolkerstorfer, S., E. Schwaiger, M. Rinnerthaler, I. Karina Gratz, T. Zoegg, H. Brandstetter and G. Achatz-Straussberger. "Hax1 Deletion Impairs Bcr Internalization and Leads to Delayed Bcr-Mediated Apoptosis." (2015) Cell Mol Immunol

Pichler, U., M. Hauser, M. Wolf, M. L. Bernardi, G. Gadermaier, R. Weiss, C. Ebner, H. Yokoi, T. Takai, A. Didierlaurent, C. Rafaiani, P. Briza, A. Mari, H. Behrendt, M. Wallner and F. Ferreira. "Pectate Lyase Pollen Allergens: Sensitization Profiles and Cross-Reactivity Pattern." (2015) PLoS One 10, no. 5 

Diesner, S. C., C. Schultz, C. Ackaert, G. J. Oostingh, A. Ondracek, C. Stremnitzer, J. Singer, D. Heiden, F. Roth-Walter, J. Fazekas, V. E. Assmann, E. Jensen-Jarolim, H. Stutz, A. Duschl and E. Untersmayr. "Nitration of Beta-Lactoglobulin but Not of Ovomucoid Enhances Anaphylactic Responses in Food Allergic Mice." (2015) PLoS One 10, no. 5

Weber CS, Hainz K, Deressa T, Strandt H, Florindo Pinheiro D, Mittermair R, Pizarro Pesado J, Thalhamer J, Hammerl P, Stoecklinger A. "Immune Reactions against Gene Gun Vaccines Are Differentially Modulated by Distinct Dendritic Cell Subsets in the Skin." (2015) PLoS One  1;10(6)

Hinterseer E, Stiefel O, Neureiter D, Kandler G, Vogt S, Hutter J, Strasser G, Greil R, Hartmann TN, Hopfinger G. "VLA-4 and CXCR4 overexpression in bone marrow of an aleukemic B-cell acute lymphoblastic leukemia presenting with osteolytic bone lesions." (2015) Leuk Lymphoma.

Hutterer E, Asslaber D, Caldana C, Krenn PW, Zucchetto A, Gattei V, Greil R, Hartmann TN. "CD18 (ITGB2) expression in chronic lymphocytic leukaemia is regulated by DNA methylation-dependent and -independent mechanisms." (2015) Br J Haematol.

Ganghammer S, Hutterer E, Hinterseer E, Brachtl G, Asslaber D, Krenn PW, Girbl T, Berghammer P, Geisberger R, Egle A, Zucchetto A, Kruschinski A, Gattei V, Chigaev A, Greil R, Hartmann TN. "CXCL12-induced VLA-4 activation is impaired in trisomy 12 chronic lymphocytic leukemia cells: a role for CCL21." (2015) Oncotarget.

D Kern, G Regl, SW Hofbauer, P Altenhofer, G Achatz, A Dlugosz, H Schnidar, R Greil, TN Hartmann and F Aberger. "Hedgehog/GLI and PI3K signaling in the initiation and maintenance of chronic lymphocytic leukemia" (2015) Oncogene 1–11

Kitzmuller, C., N. Zulehner, A. Roulias, P. Briza, F. Ferreira, I. Fae, G. F. Fischer and B. Bohle. "Correlation of Sensitizing Capacity and T-Cell Recognition within the Bet V 1 Family" (2015) J Allergy Clin Immunol

2014

Girbl T, Lunzer V, Greil R, Namberger K, Hartmann TN. "The CXCR4 and adhesion molecule expression of CD34+ hematopoietic cells mobilized by "on-demand" addition of plerixafor to granulocyte-colony-stimulating factor." (2014) Transfusion.

Skala, W., D. T. Utzschneider, V. Magdolen, M. Debela, S. Guo, C. S. Craik, H. Brandstetter and P. Goettig. "Structure-Function Analyses of Human Kallikrein-Related Peptidase 2 Establish the 99-Loop as Master Regulator of Activity." (2014) J Biol Chem 289; 49, 34267-83.

Grutsch, S., J. E. Fuchs, R. Freier, S. Kofler, M. Bibi, C. Asam, M. Wallner, F. Ferreira, H. Brandstetter, K. R. Liedl and M. Tollinger. "Ligand Binding Modulates the Structural Dynamics and Compactness of the Major Birch Pollen Allergen." Biophys J 107, no. 12 (2014): 2963-72. 

Guo S, Skala W, Magdolen V, Brandstetter H, Goettig P. "Sweetened kallikrein-related peptidases (KLKs): glycan trees as potential regulators of activation and activity." Biol Chem. (2014)

Ferreira, F., M. Wolf and M. Wallner. "Molecular Approach to Allergy Diagnosis and Therapy." Yonsei Med J 55, no. 4 (2014): 839-52

Asam C., A. L. Batista, A. H. Moraes, V. S. de Paula, F. C. Almeida, L. Aglas, C. Kitzmuller, B. Bohle, C. Ebner, F. Ferreira, M. Wallner and A. P. Valente. "Bet V 1 - a Trojan Horse for Small Ligands Boosting Allergic Sensitization?" (2014) Clin Exp Allergy, 44(8)

Isakovic A, Weiss R, Thalhamer J, Scheiblhofer S. "Protective and therapeutic DNA vaccination against allergic diseases." (2014) Methods Mol Biol., 1143:243-258

C. Ackaert, S. Kofler, J. Horejs-Höck, N. Zulehner, G. Posselt, S. von Grafenstein, K. Liedl, B. Bohle, F. Ferreira, H. Brandstetter, A. Duschl, G.J. Oostingh. "Impact of nitration on the immunogenicity and structure of Bet v 1.0101." (2014) PLoS One. 15;9(8)

S. Kofler, C. Ackaert, M. Samonig, C. Asam, P. Briza, J. Horejs-Höck, C. Cabrele, F. Ferreira, A. Duschl, C. Huber, H. Brandstetter. "Stabilization of the dimeric birch pollen allergen Bet v 1 impacts its immunological properties." (2014) J Biol. Chem. 289(1):540-51

K. Reinmuth-Selzle, C. Ackaert, M. Samonig, C. J. Kampf, M. Shiraiwa, S. Kofler, G. Gadermaier, H. Brandstetter, C. Huber, G. J. Oostingh, A. Duschl, U. Pöschl. "Nitration of the birch pollen allergen Bet v 1.0101 by liquid and gaseous nitrating agents: nitration efficiency and site-specific quantification." (2014) J Proteome Res. 13(3):1570-7

E. Groessinger, L. Weiss, S. Zierler, S. Rebhandl, P. Krenn, E. Hinterseer, J. Schmoelzer, D. Asslaber, S. Hainzl, D. Neureiter, A. Egle, J. Piñón Hofbauer, T. N. Hartmann, R. Greil, and H. Kerschbaum. "Targeting proliferation of chronic lymphocytic leukemia (CLL) cells through KCa3.1 blockade." (2014) Leukemia 28(4):954-8

Muth T, Weilnböck L, Rapp E, Huber CG, Martens L, Vaudel M, Barsnes H. "DeNovoGUI: An Open Source Graphical User Interface for de Novo Sequencing of Tandem Mass Spectra." (2014) J Proteome Res 13(2):1143-6.

Gadermaier G., Eichhorn S., Vejvar E., Weilnböck L., Lang R., Briza P., Hawranek T., Huber C., Ferreira F. "Plantago lanceolata: An important trigger of summer pollinosis with limited IgE cross-reactivity." (2014) J Allergy Clin Immun

Putz E.M., Hoelzl M.A., Baeck J., Bago-Horvath Z., Schuster C., Reichholf B., Kern D., Aberger F., Sexl V., and Hoelbl-Kovacic A. "Loss of STAT3 in Lymphoma Relaxes NK Cell-Mediated Tumor Surveillance." (2014) Cancers 6, 193-210

Reinmuth-Selzle K., C. Ackaert, C. J. Kampf, M. Samonig, M. Shiraiwa, S. Kofler, H. Yang, G. Gadermaier, H. Brandstetter, C. G. Huber, A. Duschl, G. J. Oostingh, and U. Poschl. "Nitration of the birch pollen allergen Bet v 1.0101: efficiency and site-selectivity of liquid and gaseous nitrating agents." (2014) J Proteome Res 13:1570-1577.

Kofler S., C. Ackaert, M. Samonig, C. Asam, P. Briza, J. Horejs-Hoeck, C. Cabrele, F. Ferreira, A. Duschl, C. Huber, and H. Brandstetter. "Stabilization of the dimeric birch pollen allergen Bet v 1 impacts its immunological properties." (2014) J Biol Chem 289:540-551.

C. Asam, A.L. Batista, A.H. Moraes, V.S. de Paula, F.C.L. Almeida, B. Bohle, C. Ebner, F. Ferreira, M. Wallner and A.P. Valente. "Bet v 1 – a Trojan horse for small ligands boosting allergic sensitization?" (2014) Clin Exp Allergy

Roulias A, Pichler U, Hauser M, Himly M, Hofer H, Lackner P, Ebner C, Briza P, Bohle B, Egger M, Wallner M, Ferreira F. "Differences in the intrinsic immunogenicity and allergenicity of Bet v 1 and related food allergens revealed by site-directed mutagenesis." (2014) Allergy 69:208-215

Eticha T.D., A. Stoecklinger, M. Wallner, M. Himly, S. Kofler, K. Hainz, H. Brandstetter, J. Thalhamer and P. Hammerl. "Structural Integrity of the Antigen is a Determinant for the Induction of T-Helper Type-1 Immunity in Mice by Gene Gun Vaccines against E.coli beta-Galactosidase." (2014). Plos One

2013

Asslaber D, Grössinger EM, Girbl T, Hofbauer SW, Egle A, Weiss L, Greil R, Hartmann TN. "Mimicking the microenvironment in chronic lymphocytic leukaemia - where does the journey go?" (2013) Br J Haematol.

S. Gusenkov, C. Ackaert, H. Stutz. "Separation and characterization of nitrated variants of the major birch pollen allergen by CZE-ESI-μTOF MS." (2013) Electrophoresis, 34(18):2695-704.

K. Selzle, C. Ackaert, C. J. Kampf, A. T. Kunert, G. J. Oostingh,  A. Duschl, U. Pöschl. "Determination of nitration degrees for the birch pollen allergen Bet v 1.0101." (2013) Anal Bioanal Chem. 405(27):8945-9.

Girbl T, Hinterseer E, Grössinger EM, Asslaber D, Oberascher K, Weiss L, Hauser-Kronberger C, Neureiter D, Kerschbaum H, Naor D, Alon R, Greil R, Hartmann TN. "CD40-mediated activation of chronic lymphocytic leukemia cells promotes their CD44-dependent adhesion to hyaluronan and restricts CCL21-induced motility." (2013) Cancer Res. 73(2):561-70.

P. Pollheimer, B. Taskinen, A. Scherfler, S. Gusenkov, M. Creus, P. Wiesauer, D. Zauner, W. Schöfberger, C. Schwarzinger, A. Ebner, R. Tampé, H. Stutz, V.P. Hytönen, H.J. Gruber. "Reversible biofunctionalization of surfaces with switchable mutant of avidin." (2013) Bioconjugate Chemistry, 24(10), 1656-1668.

Weinberger E.E., Isakovic A., Scheiblhofer S., Ramsauer C., Reiter K., Hauser-Kronberger C., Thalhamer J., Weiss R. "The influence of antigen targeting to sub-cellular compartments on the anti-allergic potential of a DNA vaccine." (2013) Vaccine 31(51):6113-6121.

Weinberger E.E., Himly M., Myschik J., Hauser M., Altmann F., Isakovic A., Scheiblhofer S., Thalhamer J., Weiss R.  "Generation of hypoallergenic neoglycoconjugates for dendritic cell targeted vaccination: a novel tool for specific immunotherapy." (2013) J Control Release 165(2):101-109

Weiss R., Scheiblhofer S., Machado Y., Thalhamer J.  "New approaches to transcutaneous immunotherapy: targeting dendritic cells with novel allergen conjugates." (2013) Curr Opin Allergy Clin Immunol 13(6):669-676

Schwarz H, Posselt G, Wurm P, Ulbing M, Duschl A, Horejs-Hoeck J. "TLR8 and NOD signaling synergistically induce the production of IL-1β and IL-23 in monocyte-derived DCs and enhance the expression of the feedback inhibitor SOCS2." (2013) Immunobiology 218(4):533-42.

Wolff F, Loipetzberger A, Gruber W, Esterbauer H, Aberger F, Frischauf AM. "Imiquimod directly inhibits Hedgehog signalling by stimulating adenosine receptor/protein kinase A-mediated GLI phosphorylation." (2013) Oncogene 32(50):5574-81

Wenger J, Klinglmayr E, Fröhlich C, Eibl C, Gimeno A, Hessenberger M, Puehringer S, Daumke O, Goettig P. "Functional mapping of human dynamin-1-like GTPase domain based on x-ray structure analyses." (2013) PLoS One. 8(8):e71835

Eckhard U., E. Schönauer, and H. Brandstetter. "Structural basis for activity regulation and substrate preference of clostridial collagenases G, H, and T." (2013) J Biol Chem 288:20184-20194

Pichler U, Asam C, Weiss R, Isakovic A, Hauser M, Briza P, Ferreira F, Wallner M. "The Fold Variant BM4 Is Beneficial in a Therapeutic Bet v 1 Mouse Model." (2013) Biomed Res Int 

Weinberger EE., Isakovic A., Scheiblhofer S., Ramsauer Ch., Reiter K., Hauser-Kronberger C., Thalhamer J., Weiss R. "The influence of antigen targeting to sub-cellular compartments on the anti-allergic potential of a DNA vaccine." (2013) Vaccine 31(51):6113-21.

Weinberger E.E., Himly M., Myschik J., Hauser M., Altmann F., Isakovic A., Scheiblhofer S., Thalhamer J., Weiss R. "Generation of hypoallergenic neoglycoconjugates for dendritic cell targeted vaccination: a novel tool for specific immunotherapy." (2013) J Control Release 165(2):101-109.

Hessenberger M, Weiss R, Weinberger EE, Boehler C, Thalhamer J, Scheiblhofer S. "Transcutaneous delivery of CpG-adjuvanted allergen via laser-generated micropores."  (2013) Vaccine. 31(34):3427-34

2012

Pichler P, Mazanek M, Dusberger F, Weilnböck L, Huber CG, Stingl C, Luider TM, Straube WL, Köcher T, Mechtler K. "SIMPATIQCO: a server-based software suite which facilitates monitoring the time course of LC-MS performance metrics on Orbitrap instruments." (2012) J Proteome Res. 11(11):5540-7.

A. Zucchetto, C. Caldana, D. Benedetti, E. Tissino, F. M. Rossi, E. Hutterer, F. Pozzo, R. Bomben, M. Dal Bo, G. D’Arena, F. Zaja, G. Pozzato, F. Di Raimondo, T. N. Hartmann, D. Rossi, G. Gaidano, G. Del Poeta, V. Gattei. "Trisomy 12 is associated with CD49d overexpression in chronic lymphocytic leukemia: evidence for a methylation-dependent mechanism of regulation." (2012) Blood 122(19):3317-21.

Rieder G, Krisch L, Fischer H, Kaufmann M, Maringer A, Wessler S. "Carnobacterium divergens - a dominating bacterium of pork meat juice." (2012) FEMS Microbiol Lett, 332: 122-130.

Horejs-Hoeck J, Schwarz H, Lamprecht S, Maier E, Hainzl S, Schmittner M, Posselt G, Stoecklinger A, Hawranek T, Duschl A. "Dendritic cells activated by IFN-γ/STAT1 express IL-31 receptor and release proinflammatory mediators upon IL-31 treatment." (2012) J Immunol. 188(11):5319-26.

Eibl C, Grigoriu S, Hessenberger M, Wenger J, Puehringer S, Pinheiro AS, Wagner RN, Proell M, Reed JC, Page R, Diederichs K, Peti W. "Structural and functional analysis of the NLRP4 pyrin domain." (2012) Biochemistry 51(37):7330-41.

Stoecklinger A, Scheiblhofer S, Roesler E, Lang A, Fastner G, Sedlmayer F, Lang R, Danzer M, Thalhamer J, Weiss R. "T cell epitopes of the timothy grass pollen allergen Phl p 5 of mice and men and the detection of allergen-specific T cells using Class II Ultimers." (2012) Int Arch Allergy Immunol. 158(4):326-34.

Weiss R, Scheiblhofer S, Roesler E, Weinberger E, Thalhamer J. "mRNA vaccination as a safe approach for specific protection from type I allergy." (2012) J. Expert Rev Vaccines 11(1):55-67.

Aberger F., Kern D., Greil R., and Hartmann T.N. "Canonical and noncanonical Hedgehog/GLI signaling in hematological malignancies." (2012) Vitam Horm 88, 25-54.

Mangelberger D., Kern D., Loipetzberger A., Eberl M., and Aberger F. "Cooperative Hedgehog-EGFR signaling." (2012)  Front Biosci 17, 90-99

Eberl, M., Klingler, S., Mangelberger D., Loipetzberger A., Damhofer H., Zoidl K., Schnidar H., Hache H., Bauer H.C., Solca F., Hauser-Kronberger C., Ermilov A.N., Verhaegen M.E., Bichakjian C.K., Dlugosz A.A., Nietfeld W., Sibilia M., Lehrach H., Wierling C., and Aberger F. "Hedgehog-EGFR cooperation response genes determine the oncogenic phenotype of basal cell carcinoma and tumour-initiating pancreatic cancer cells." (2012) EMBO Mol Med 4, 218-233.

Kofler S., C. Asam, U. Eckhard, M. Wallner, F. Ferreira, and H. Brandstetter. "Crystallographically mapped ligand binding differs in high and low IgE binding isoforms of birch pollen allergen bet v 1." (2012) J Mol Biol 422:109-123.

Bach D, Weiss R, Hessenberger M, Kitzmueller S, Weinberger EE, Krautgartner WD, Hauser-Kronberger C, Boehler C, Thalhamer J, Scheiblhofer S. "Transcutaneous immunotherapy via laser-generated micropores: a comparison with subcutaneous immunotherapy in a Phl p 5 mouse model of allergic asthma." (2012) Allergy. 67(11):1165-74.

Weiss R, Hessenberger M, Kitzmueller S, Bach D, Weinberger EE, Krautgartner WD, Hauser-Kronberger C, Malissen B, Boehler C, Kalia YN, Thalhamer J, Scheiblhofer S. "Transcutaneous vaccination via laser microporation." (2012) Journal of Controlled Release 162(2):391-399.

2011

Audisio D., Messaoudi S., Cegielkowski L., Peyrat J.F., Brion J.D., Methy-Gonnot D., Radanyi C., Renoir J.M., and Alami M.  "Discovery and biological activity of 6BrCaQ as an inhibitor of the Hsp90 protein folding machinery." (2011) ChemMedChem 6, 804-815.

Boraschi D, Lucchesi D, Hainzl S, Leitner M, Maier E, Mangelberger D, Oostingh GJ, Pfaller T, Pixner C, Posselt G, Italiani P, Nold MF, Nold-Petry CA, Bufler P, Dinarello CA. "IL-37: a new anti-inflammatory cytokine of the IL-1 family." (2011) Eur Cytokine Netw. 22(3):127-47.

Posselt G, Schwarz H, Duschl A, Horejs-Hoeck J. "Suppressor of cytokine signaling 2 is a feedback inhibitor of TLR-induced activation in human monocyte-derived dendritic cells."  (2011) J Immunol. 187(6):2875-84.

Maier E, Hebenstreit D, Posselt G, Hammerl P, Duschl A, Horejs-Hoeck J. "Inhibition of suppressive T cell factor 1 (TCF-1) isoforms in naive CD4+ T cells is mediated by IL-4/STAT6 signaling." (2011) J Biol Chem. 286(2):919-28.

Pinheiro AS, Eibl C, Ekman-Vural Z, Schwarzenbacher R, Peti W. "The NLRP12 pyrin domain: structure, dynamics, and functional insights." (2011) J Mol Biol. 413(4):790-8

Eckhard U., E. Schönauer, D. Nuss, and H. Brandstetter. "Structure of collagenase G reveals a chew-and-digest mechanism of bacterial collagenolysis." (2011) Nat Struct Mol Biol 18:1109-1114.

Hauser M, Asam C, Himly M, Palazzo P, Voltolini S, Montanari C, Briza P, Bernardi ML, Mari A, Ferreira F, Wallner M. "Bet v 1-like pollen allergens of multiple Fagales species can sensitize atopic individuals." (2011) Clin Exp Allergy 41(12):1804-14

Wallner M, Hauser M, Himly M, Zaborsky N, Mutschlechner S, Harrer A, Asam C, Pichler U, van Ree R, Briza P, Thalhamer J, Bohle B, Achatz G, Ferreira F. "Reshaping the Bet v 1 fold modulates T(H) polarization." (2011) J Allergy Clin Immunol. 127(6):1571-8

Erler A, Hawranek T, Krückemeier L, Asam C, Egger M, Ferreira F, Briza P. "Proteomic profiling of birch (Betula verrucosa) pollen extracts from different origins." (2011) Proteomics 11(8):1486-98

Stoecklinger A., T. D. Eticha, M. Mesdaghi, A. Kissenpfennig, B. Malissen, J. Thalhamer, and P. Hammerl. "Langerin+ Dermal Dendritic Cells Are Critical for CD8+ T Cell Activation and IgH {gamma}-1 Class Switching in Response to Gene Gun Vaccines." (2011) J Immunol. 186:1377-83.

2010

Pinheiro AS, Proell M, Eibl C, Page R, Schwarzenbacher R, Peti W. "Three-dimensional structure of the NLRP7 pyrin domain: insight into pyrin-pyrin-mediated effector domain signaling in innate immunity." (2010) J Biol Chem. 285(35):27402-10

Weiss R, Scheiblhofer S, Roesler E, Ferreira F, Thalhamer J. "Prophylactic mRNA vaccination against allergy." (2010) J. Curr Opin Allergy Clin Immunol. 10(6):567-74.

Desch P., Asslaber D., Kern D., Schnidar H., Mangelberger D., Alinger, B., Stoecher, M., Hofbauer, S.W., Neureiter, D., Tinhofer, I., et al. "Inhibition of GLI, but not Smoothened, induces apoptosis in chronic lymphocytic leukemia cells." (2010) Oncogene 29, 4885-4895.

Hauser M, Roulias A, Ferreira F, Egger M. "Panallergens and their impact on the allergic patient." (2010) Allergy, Asthma & Clinical Immunology 6:1,

Peckl-Schmid D, Wolkerstorfer S, Königsberger S, Achatz-Straussberger G, Feichtner S, Schwaiger E, Zaborsky N, Huemer M, Gratz IK, Schibli R, Lamers M, Crameri R, Moser K, Luger EO, Achatz G. "HAX1 deficiency: impact on lymphopoiesis and B-cell development." (2010) Eur J Immunol. 40(11):3161-72

2009

Roesler E, Weiss R, Weinberger EE, Fruehwirth A, Stoecklinger A, Mostböck S, Ferreira F, Thalhamer J, Scheiblhofer S. "Immunize and disappear-safety-optimized mRNA vaccination with a panel of 29 allergens." (2009) J Allergy Clin Immunol. 124(5):1070-7.

Schnidar H., Eberl M., Klingler S., Mangelberger D., Kasper M., Hauser-Kronberger C., Regl G., Kroismayr R., Moriggl R., Sibilia M., and Aberger F. "Epidermal growth factor receptor signaling synergizes with Hedgehog/GLI in oncogenic transformation via activation of the MEK/ERK/JUN pathway." (2009). Cancer Res 69, 1284-1292.

Schönauer E, U. Eckhard, U.P. Ducka, P. Briza, D. Nuss, and H. Brandstetter. "Biochemical characterization of the catalytic domains of three different Clostridial collagenases." (2009) Biol Chem 390:11-18

Schönauer E., P. Ducka U. Eckhard S. Kofler G. Gottschalk H. Brandstetter H. and D. Nuss. "A universal strategy for high-yield production of soluble and functional clostridial collagenases in E. coli." (2009) Appl Microbiol Biotechnol 83:1055-1065.

Wallner M, Himly M, Neubauer A, Erler A, Hauser M, Asam C, Mutschlechner S, Ebner C, Briza P, Ferreira F. "The influence of recombinant production on the immunologic behavior of birch pollen isoallergens." (2009) PLoS One 4(12)

2008

Eichberger T, Kaser A, Pixner C, Schmid C, Klingler S, Winklmayr M, Hauser-Kronberger C, Aberger F, Frischauf AM. "GLI2-specific transcriptional activation of the bone morphogenetic protein/activin antagonist follistatin in human epidermal cells." (2008) J Biol Chem. 283(18):12426-37.

Eckhard U., D. Nuss, P. Ducka, E. Schönauer, and H. Brandstetter. "Crystallization and preliminary X-ray characterization of the catalytic domain of collagenase G from Clostridium histolyticum." (2008) Acta Crystallogr Sect F Struct Biol Cryst Commun 64:419-421

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